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Vasitis nodosa and associated clinical findings
L Hirschowitz1, J Rode, J Guillebaud
1Bland-Sutton Institute of Pathology, University College, London.
Journal of Clinical Pathology
|April 1, 1988
Summary
Vasitis nodosa affects half of vasectomy reversal patients, characterized by ductal changes and nerve alterations. This condition does not appear to impact fertility restoration outcomes.
Area of Science:
- Urology
- Reproductive Medicine
- Pathology
Background:
- Vasectomy is a common male sterilization procedure.
- Vasitis nodosa is a potential complication following vasectomy.
Purpose of the Study:
- To determine the prevalence of vasitis nodosa in patients undergoing vasectomy reversal.
- To correlate histological findings with clinical history and outcomes.
Main Methods:
- Histological and immunohistochemical examination of vas deferens segments from 40 patients undergoing reversal.
- Comparison with control segments from vasectomy procedures.
- Correlation with clinical data and postoperative fertility outcomes.
Main Results:
- Vasitis nodosa was present in 20 of 40 (50%) vasectomy reversal specimens.
- Associated findings included sperm granulomas (13 cases) and spermatocoeles (2 cases).
- Vasitis nodosa showed ductal proliferation and mucinous metaplasia; nerve fiber hyperplasia and neuromas were observed in affected cases.
Conclusions:
- Vasitis nodosa is a common finding after vasectomy.
- Histological changes include ductal and neural alterations.
- The presence of vasitis nodosa did not affect fertility restoration after vasectomy reversal.