CT appearance of focal pseudomembranous colitis

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J R Yankes1, M E Baker, C Cooper

  • 1Department of Radiology, Duke University Medical Center, Durham, NC 27710.

Insights

Focal pseudomembranous colitis (PMC) can appear as localized colonic thickening on CT scans, a presentation not commonly emphasized in radiology reports. This study highlights three such cases, expanding the known CT spectrum of PMC.

Area of Science:

  • Radiology
  • Gastroenterology
  • Pathology

Background:

  • Pseudomembranous colitis (PMC) is typically associated with diffuse colonic involvement in prior computed tomography (CT) imaging studies.
  • The focal manifestation of PMC, while recognized in clinical gastroenterology, has been underrepresented in radiological literature concerning CT findings.

Observation:

  • This report details three distinct cases where focal colonic thickening was identified on CT scans.
  • These focal abnormalities were subsequently diagnosed as pseudomembranous colitis upon further investigation.

Findings:

  • Computed tomography (CT) can reveal focal colonic wall thickening as a presentation of pseudomembranous colitis (PMC).
  • This finding challenges the traditional understanding of PMC CT imaging, which often emphasizes diffuse disease patterns.

Implications:

  • Radiologists should consider focal colonic thickening as a potential CT sign of pseudomembranous colitis (PMC).
  • Increased awareness of this focal manifestation may improve diagnostic accuracy and timely treatment initiation for PMC.
  • This expands the spectrum of imaging findings for PMC, aiding in differential diagnosis.

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