Related Experiment Video
Updated: Nov 15, 2025

Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
Published on: February 23, 2024
Incisor Occlusion Affects Profile Shape Variation in Middle-Aged Adults
Georgios Kanavakis1,2,3, Anna-Sofia Silvola3,4, Demetrios Halazonetis5
1Department of Pediatric Oral Health and Orthodontics, UZB-University Center for Dental Medicine, University of Basel, Mattenstrasse 40, CH-4058 Basel, Switzerland.
Overjet and overbite significantly impact facial profile shape in middle-aged adults. These incisor occlusion traits explain a substantial portion of profile variations, highlighting their importance in facial morphology.
Area of Science:
- Orthodontics and Dental Morphology
- Anthropometry and Biomechanics
- Genetics and Environmental Influences on Craniofacial Development
Background:
- Understanding the relationship between dental occlusion and facial aesthetics is crucial in orthodontics.
- Middle-aged individuals represent a key demographic for studying long-term effects of occlusion on facial structure.
- Previous research has explored various factors influencing soft tissue profile, but the specific impact of overjet and overbite requires further elucidation.
Purpose of the Study:
- To quantify the effect of overjet and overbite on the soft tissue profile in a middle-aged cohort.
- To determine the relative contributions of overjet and overbite to overall profile shape variation.
- To investigate potential sex-based differences in the influence of these occlusal parameters on facial morphology.
Main Methods:
- Utilized a large cohort (n=1754) from the 1966 Northern Finland Birth Cohort at age 46.
- Employed 3D stereophotogrammetry with 48 landmarks and semi-landmarks for precise profile digitization.
- Applied Procrustes Superimposition and Principal Component Analysis (PCA) for shape analysis, with multivariate regression to assess occlusal effects.
Main Results:
- The first nine Principal Components (PCs) captured over 90% of profile shape variance.
- Overjet was a significant predictor of profile shape, accounting for 21.3% of variation (p < 0.001).
- Overbite had a weaker but still significant effect, explaining 13.8% of variation (p < 0.001), with notable sex differences observed.
Conclusions:
- Incisor occlusion, specifically overjet and overbite, significantly influences the soft tissue profile in middle-aged adults.
- The substantial impact of occlusion on profile shape underscores its importance, especially considering the interplay of genetic and environmental factors.
- These findings have implications for orthodontic diagnosis, treatment planning, and understanding craniofacial development.
Related Concept Videos
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Facial Feedback Hypothesis
Prosopagnosia
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...

