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Published on: June 24, 2020
Simultaneous Occurrence of Choriocarcinoma in an Infant and Mother
Małgorzata Rzanny-Owczarzak1, Joanna Sawicka-Metkowska2, Katarzyna Jończyk-Potoczna3
1Department of Pediatric Surgery, Traumatology and Urology, Poznan University of Medical Sciences, 60-572 Poznań, Poland.
Insights
Infantile choriocarcinoma is a rare cancer. A simultaneous diagnosis in a mother and infant highlights the need for early human chorionic gonadotropin (hCG) testing in newborns with anemia or liver tumors.
Area of Science:
- Oncology
- Pediatrics
- Maternal-Fetal Medicine
Background:
- Infantile choriocarcinoma is an exceptionally rare malignancy.
- Simultaneous diagnosis in a neonate and mother is exceedingly uncommon.
- Advanced disease presentation in neonates often leads to poor outcomes.
Abstract:
Infantile choriocarcinoma is an extremely rare disease. We present a case study of a 1-month-old male with choriocarcinoma diagnosed simultaneously with his mother. On admission to hospital, the disease was very advanced and massive progression and multi-organ failure caused the death of the patient despite the implemented treatment. It was too late to save the child's life, but early enough to save his mother. The authors believe that the serum levels of hCG should be determined in every newborn with anemia and liver tumor, especially when the mother has a positive history of miscarriage.
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