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Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty
Daniel C Santana1, Matthew J Hadad1, Ahmed Emara1
1Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USA.
Insights
Managing antithrombotic agents is crucial for patients undergoing total joint arthroplasty (TJA). This review overviews guidelines for perioperative antithrombotic management in elective TJAs.
Area of Science:
- Orthopedic Surgery
- Cardiology
- Hematology
Background:
- Total hip and knee arthroplasty (TJA) are increasingly common orthopedic procedures.
- Many TJA patients use chronic antithrombotic agents for conditions like atrial fibrillation or acute coronary syndrome.
- Perioperative antithrombotic management is critical due to bleeding risks from TJA and thromboembolic risks post-surgery.
Purpose of the Study:
- To provide an overview of current society guidelines for perioperative antithrombotic management in elective TJA.
- To summarize recent literature relevant to informing future guidelines on antithrombotic management.
- To emphasize the importance of patient-specific, multidisciplinary approaches to antithrombotic therapy.
Main Methods:
- Review of existing society guidelines on perioperative antithrombotic management for TJA.
- Synthesis of recent scientific literature concerning antithrombotic therapy in the context of TJA.
- Consultation with cardiology, internal medicine, and hematology specialists.
Main Results:
- Established guidelines offer frameworks for managing antithrombotic agents during TJA.
- Recent literature highlights evolving strategies and considerations for perioperative antithrombotic use.
- A patient-specific approach, involving multiple medical specialties, is essential for optimal outcomes.
Conclusions:
- Perioperative antithrombotic management in TJA requires careful consideration of bleeding and thromboembolic risks.
- Adherence to guidelines and incorporation of recent literature are vital for safe and effective patient care.
- Collaborative, patient-centered decision-making among various medical specialists ensures optimal management of antithrombotic regimens.
Abstract:
Total hip and knee arthroplasty are common major orthopedic operations being performed on an increasing number of patients. Many patients undergoing total joint arthroplasty (TJA) are on chronic antithrombotic agents due to other medical conditions, such as atrial fibrillation or acute coronary syndrome. Given the risk of bleeding associated with TJAs, as well as the risk of thromboembolic events in the post-operative period, the management of chronic antithrombotic agents perioperatively is critical to achieving successful outcomes in arthroplasty. In this review, we provide a concise overview of society guidelines regarding the perioperative management of chronic antithrombotic agents in the setting of elective TJAs and summarize the recent literature that may inform future guidelines. Ultimately, antithrombotic regimen management should be patient-specific, in consultation with cardiology, internal medicine, hematology, and other physicians who play an essential role in perioperative care.
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