Related Experiment Video
Updated: Nov 15, 2025

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
Published on: September 9, 2022
Alexithymia in Patients with Ménière Disease: A Possible Role on Anxiety and Depression
Roberto Teggi1, Claudia Yvonne Finocchiaro2,3, Claudio Ruggieri2
1ENT Division, Department of ENT, IRCCS San Raffaele Hospital, 20132 Milan, Italy.
Abstract:
The aim of this paper was to investigate the role of the psychological variable of alexithymia both as a risk factor for the development of Ménière's disease (MD) and as a component that influences the personal experience of MD and the individual quality of life. We collected data from 179 Italian patients who fulfilled criteria for definite MD. Patients filled out validated self-rating questionnaires to assess alexithymia (TAS-20), quality of life (WHOQOL-BREF), anxiety and depression (HADS), perception of stress (PSS) and coping strategies (COPE). Socio-demographic data and MD clinical features were collected using a specific rating form. Subjects affected by MD showed higher levels of alexithymia compared to general population. Among MD patients, those characterized by high levels of alexithymia revealed a significant increase in anxiety and depression, greater perceived stress, a lower quality of life in psychological health and social relationships domains and the use of less mature coping strategies in comparison with MD patients with low or absent alexithymia. Our preliminary data could help in hypothesizing a role of psychological functioning in MD development and in the adaptation to the disease. The presence of alexithymia in patients suffering from MD may constitute a risk factor for the development of anxiety and depression symptoms; greater perceived stress and for poorer psychological and relational quality of life. Therefore, our study design did not allow causal inferences and further studies are needed.
Insights
Alexithymia, difficulty identifying emotions, is linked to Ménière
Area of Science:
- Psychology
- Otolaryngology
- Psychosomatic Medicine
Background:
- Ménière's disease (MD) is a disorder of the inner ear.
- The psychological factors influencing MD are not fully understood.
Purpose of the Study:
- To investigate alexithymia as a risk factor for MD development.
- To examine how alexithymia affects the experience and quality of life in MD patients.
Main Methods:
- 179 Italian MD patients completed validated questionnaires.
- Assessed alexithymia (TAS-20), quality of life (WHOQOL-BREF), anxiety/depression (HADS), stress (PSS), and coping (COPE).
Main Results:
- MD patients exhibited higher alexithymia levels than the general population.
- High alexithymia in MD patients correlated with increased anxiety, depression, stress, and lower quality of life.
- Patients with high alexithymia used less adaptive coping strategies.
Conclusions:
- Alexithymia may play a role in MD development and adaptation.
- Alexithymia could be a risk factor for psychological distress and reduced quality of life in MD patients.
- Further research is needed to establish causality.
Related Concept Videos
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Depressive Disorders: MDD and Dysthymia
Depression: Overview
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Self-Discrepancy and Its Effects

