Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

295
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
295

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cellular immune response of Amblyomma sculptum and Amblyomma americanum to entomopathogenic fungi: Implications for biological tick control.

Medical and veterinary entomology·2026
Same author

Identification of Potential <i>Amblyomma americanum</i> Antigens After Vaccination with Tick Extracellular Vesicles in White-Tailed Deer.

Vaccines·2025
Same author

Validation of a heat-inducible <i>Ixodes scapularis</i> HSP70 promoter and developing a tick-specific 3xP3 promoter sequence in ISE6 cells.

bioRxiv : the preprint server for biology·2023
Same author

Evaluation of the in vitro acaricidal effect of five organic compounds on the cattle fever tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae).

Experimental & applied acarology·2023
Same author

<i>Anaplasma phagocytophilum</i> Transmission Activates Immune Pathways While Repressing Wound Healing in the Skin.

Life (Basel, Switzerland)·2022
Same author

<i>Wolbachia</i> Impacts <i>Anaplasma</i> Infection in <i>Ixodes scapularis</i> Tick Cells.

International journal of environmental research and public health·2022
Same journal

Correction: Grewal et al. Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications. <i>Int. J. Environ. Res. Public Health</i> 2026, <i>23</i>, 241.

International journal of environmental research and public health·2026
Same journal

Drinking Water Quality and Health Risk Assessment in Rural Ghana: Evidence from North-East and North Gonja Districts in the Savannah Region.

International journal of environmental research and public health·2026
Same journal

Physical Activity of University Students During COVID-19 Restrictions: Evidence from Poland.

International journal of environmental research and public health·2026
Same journal

Assessment of Occupational Health and Safety Hazards in Mosquito Control Personnel in North Carolina and Virginia, USA.

International journal of environmental research and public health·2026
Same journal

Association Between Dysfunctional Parenting Practices and Suspected Gaming Disorder Among Japanese Male Junior High School Students: A Cross-Sectional Study of Parental Assessment.

International journal of environmental research and public health·2026
Same journal

A National Virtual Peer Support Group for Women Veterans Living with Breast Cancer: Lessons from the Field.

International journal of environmental research and public health·2026
See all related articles

Related Experiment Video

Updated: Nov 15, 2025

Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)
04:42

Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)

Published on: October 31, 2025

131

Changing the Recipe: Pathogen Directed Changes in Tick Saliva Components.

Michael Pham1, Jacob Underwood1, Adela S Oliva Chávez1

  • 1Department of Entomology, College Station, Texas A&M University, TX 77843, USA.

International Journal of Environmental Research and Public Health
|March 6, 2021
PubMed
Summary
This summary is machine-generated.

Ticks secrete saliva molecules to feed and transmit pathogens like Lyme disease bacteria. These molecules help pathogens survive and evade host defenses, impacting disease transmission.

Keywords:
Anaplasma phagocytophilumBorrelia burgdorferisaliva-assisted transmissiontick salivatick-borne diseasestick-borne encephalitisticks

More Related Videos

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks
08:16

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Published on: February 21, 2012

30.2K
Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles
08:03

Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles

Published on: April 6, 2022

2.8K

Related Experiment Videos

Last Updated: Nov 15, 2025

Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)
04:42

Extraction of Saliva, Haemolymph, Salivary Glands, and Midgut from Individual Ticks (Acari: Ixodidae)

Published on: October 31, 2025

131
Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks
08:16

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Published on: February 21, 2012

30.2K
Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles
08:03

Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles

Published on: April 6, 2022

2.8K

Area of Science:

  • Parasitology
  • Immunology
  • Molecular Biology

Background:

  • Ticks are obligate hematophagous parasites and vectors of numerous pathogens.
  • Hard ticks require prolonged feeding, necessitating counteraction of host defense mechanisms.
  • Tick saliva contains bioactive molecules that modulate host immunity and wound healing.

Purpose of the Study:

  • To review characterized tick saliva molecules and their role in pathogen infection.
  • To examine pathogen manipulation of tick saliva for enhanced survival and transmission.
  • To discuss sialome-level responses to pathogen challenge in ticks.

Main Methods:

  • Literature review of studies on tick saliva molecules.
  • Analysis of specific tick-borne pathogens including Borrelia, Anaplasma phagocytophilum, and tick-borne encephalitis virus.
  • Review of sialome-level responses to pathogen challenge.

Main Results:

  • Tick saliva molecules inhibit host immune responses and wound healing, creating a favorable environment for pathogens.
  • Pathogens can manipulate tick saliva composition to promote their own transmission and immune evasion.
  • Studies show altered tick sialomes in response to pathogen infection.

Conclusions:

  • Tick saliva plays a critical role in host-pathogen interactions during tick feeding.
  • Understanding tick saliva molecules is crucial for developing strategies against tick-borne diseases.
  • Pathogen manipulation of tick saliva highlights complex co-evolutionary dynamics.