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Differences between Professional and Amateur Cyclists in Endogenous Antioxidant System Profile
Francisco Javier Martínez-Noguera1, Pedro E Alcaraz1, Raquel Ortolano-Ríos1
1Research Center for High Performance Sport, Campus de los Jerónimos, Catholic University of Murcia, 30107 Murcia, Spain.
Professional cyclists show distinct endogenous antioxidant enzyme levels, including higher catalase and oxidized glutathione, compared to amateurs. These differences correlate with exercise performance in elite athletes.
Area of Science:
- Sports Science
- Biochemistry
- Exercise Physiology
Background:
- Endogenous antioxidant enzymes play a crucial role in mitigating exercise-induced oxidative stress.
- Differences in these enzymes may exist between professional and amateur athletes, potentially impacting performance.
- Limited research has explored these specific enzyme variations in cyclists.
Purpose of the Study:
- To investigate differences in endogenous antioxidant enzymes and hemogram between professional and amateur cyclists.
- To determine if observed differences in these biomarkers correlate with sports performance in cyclists.
Main Methods:
- A comparative study involving 11 professional (PRO) and 15 amateur (AMA) cyclists.
- Endogenous antioxidant analysis in a fasted state.
- Incremental exercise testing to exhaustion.
Main Results:
- Professional cyclists exhibited higher catalase (CAT), oxidized glutathione (GSSG), and GSSG/GSH ratio, with lower superoxide dismutase (SOD) compared to amateurs (p < 0.05).
- An inverse correlation was observed in PRO cyclists between power output at ventilation thresholds and the GSSG/GSH ratio (r = -0.657 and r = -0.635; p < 0.05).
Conclusions:
- No definitive endogenous antioxidant enzyme profile distinguishes professional from amateur cyclists.
- The GSSG/GSH ratio is linked to moderate and submaximal exercise performance in professional cyclists.
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