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Detection of Tissue-resident Bacteria in Bladder Biopsies by 16S rRNA Fluorescence In Situ Hybridization
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Periprosthetic joint infection with Ureaplasma parvum detected by 16S rRNA PCR

Nicola Diane Ball1, Susan Elizabeth Snape2

  • 1Infectious Diseases, Nottingham University Hospitals NHS Trust, Nottingham, UK nicola.ball7@nhs.net.

BMJ Case Reports
|March 6, 2021
PubMed

Insights

Traditional bacterial identification methods failed to detect Ureaplasma parvum in a knee joint infection. Molecular methods, like 16S ribosomal RNA PCR, enabled accurate diagnosis and targeted antimicrobial therapy, crucial for combating resistance.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Molecular Diagnostics

Background:

  • Conventional culture techniques often fail to identify fastidious bacterial pathogens.
  • Periprosthetic joint infections (PJIs) require accurate and timely diagnosis for effective treatment.
Keywords:
bone and joint infectionsinfections

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