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Ocular Surface Characteristics and Colonization in a Burn Center: A Prospective Cohort Study
Paola De La Parra-Colin1, Alejandra Gonzalez-De La Torre1, Rafael Franco-Cendejas2
1Department of Ophthalmology, Cornea and Ocular Surface Clinic, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Ministry of Health, Mexico City, Mexico.
Summary
Ocular surface colonization by pathogens and exposure keratopathy are common in burn patients. Mechanical ventilation and periocular burns increase these risks, necessitating targeted ocular care strategies.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Critical Care Medicine
Background:
- Ocular surface complications are a concern for burn patients.
- Risk factors like mechanical ventilation and periocular burns may impact ocular health.
Purpose of the Study:
- To assess ocular surface characteristics and pathogenic colonization in burn center patients.
- To determine the association of ocular issues with sedation, mechanical ventilation, and periocular burns.
Main Methods:
- Prospective evaluation of 40 burn patients over 8 months.
- Regular assessments included ocular surface parameters and conjunctival swabs for microbiology.
- Data on sedation, mechanical ventilation, and treatments were collected.
Main Results:
- Absent Bell's phenomenon and chemosis were linked to mechanical ventilation, sedation, and periocular burns.
- Cumulative incidence of exposure keratopathy was 22.5% and ocular surface colonization was 32.5%.
- Mechanical ventilation and periocular burns were associated with both outcomes. Common pathogens included Candida parapsilosis, Acinetobacter baumanii, and Pseudomonas aeruginosa.
Conclusions:
- Exposure keratopathy and pathogenic colonization are significant risks for burn patients.
- Mechanical ventilation and periocular burns are key risk factors.
- Findings support improved risk stratification and ocular surface care protocols in burn units.
