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Updated: Nov 15, 2025

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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Impact of Redefinition of Normal Limits for Echocardiographic Left Ventricular Ejection Fraction on All-Cause

Jordan B Strom1, Lawrence J Markson2, Connie W Tsao3

  • 1Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
|March 6, 2021
PubMed
Abstract

No abstract available in PubMed .

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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