Related Experiment Video
Updated: Jul 30, 2026
10:01
Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
20.8K
Pneumatosis Intestinalis Due to COVID-19 Infection in Kidney Transplant Recipient: A Case Report
D Łaski1, K Biernat1, Ł Kaska1
1General, Endocrine and Transplant Surgery Department, Medical University Gdańsk, Gdańsk, Poland.
Transplantation Proceedings
|March 8, 2021
Summary
Pneumatosis intestinalis (PI) is a rare condition linked to COVID-19, particularly in organ transplant recipients on steroids. Laparotomy with bowel resection is a safe treatment option for severe cases.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Transplant Surgery
Background:
- Pneumatosis intestinalis (PI) is a rare condition often seen in solid organ transplant recipients using steroid therapy.
- Coronavirus disease 2019 (COVID-19) utilizes angiotensin-converting enzyme 2 receptors in the gastrointestinal tract.
- Steroid use in COVID-19 patients may prolong viral presence in the GI tract, potentially increasing PI risk.
Observation:
- COVID-19 patients, especially those on steroids, may be at increased risk for developing PI.
- Pneumatosis intestinalis presents a spectrum from asymptomatic to life-threatening conditions.
- There is a lack of established diagnostic and treatment algorithms for PI.
Findings:
- A severe case of COVID-19-induced PI was observed.
- Surgical intervention, specifically laparotomy with bowel resection, was considered for this severe case.
Implications:
- Laparotomy with bowel resection can be a feasible and safe treatment for severe COVID-19-induced PI.
- Highlights the need for further research into PI management in high-risk populations.
- Emphasizes the gastrointestinal implications of COVID-19 in immunocompromised patients.
Related Concept Videos
01:30Pneumonia I: Introduction
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
01:16Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...