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Updated: Nov 15, 2025

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
Published on: October 12, 2016
Biomechanical models of in vitro constructs for spinopelvic osteosynthesis
E Sevillano-Perez1, S Postigo Pozo2, E Guerado3
1Department of Orthopaedic Surgery and Traumatology, Faculty of Medicine, University of Malaga, Autovía A-7. Km 187, 29603 Marbella, Malaga, Spain.
Abstract:
Spinopelvic lesions are the result of high-energy vertical trauma with axial skeletal overload where the spine impacts onto the sacrum, dissociating the lumbar spine from the pelvis. Therefore, lumbopelvic instrumentations are aimed to counteract these vertical forces, although various biomechanical aspects of the combinations of different constructs (with or without iliosacral screws) or the number of lumbar fixation levels (L5 or the combination of L5 with L4) are subject to controversy. The number of patients in each published series is too short, and the nature of the fixation is very different from one article to another, making comparison very difficult. In this paper the methodology for laboratory studies is discussed. The design of the test bench fixture, biomechanical testing protocol and data analysis are very important when inference to the clinical setting is desired.

