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Related Concept Videos

Nursing Ethical Principles I01:22

Nursing Ethical Principles I

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Ethical principles serve as the moral compass in the longstanding tradition of nursing, guiding healthcare professionals in their interactions with patients and families. These principles, namely autonomy, beneficence, non-maleficence, justice, and fidelity, provide a robust framework for navigating the ethical complexities of daily nursing practice.
Autonomy
Autonomy underscores the significance of a patient's self-determination and freedom from external control. In healthcare, respecting...
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Nursing Ethical Principles II01:27

Nursing Ethical Principles II

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Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
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Ethics and Bioethics01:22

Ethics and Bioethics

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Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
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Torts I01:14

Torts I

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Torts in nursing are wrongful acts that can harm patients and potentially lead to civil liability for the involved nurse. These wrongful acts range from unintentional errors to deliberate actions. Depending on the nature and severity of the tort, a nurse found liable may face financial penalties or disciplinary actions. Understanding the distinctions between intentional, quasi-intentional, and unintentional torts is crucial for nurses to mitigate risks and provide safe patient care.
Intentional...
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Professional Values01:29

Professional Values

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Nurses are responsible for caring for patients during birth, death, illness, and healing. Professional values guide the decisions and actions that nurses make in their careers. If nurses know the decisions and actions to take, providing patients with exceptional care is possible.
The values that are the foundation of the nursing profession are altruism, autonomy, human dignity, and social justice.
First, altruism refers to the concern for the welfare and well-being of others without personal...
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Nurses' Legal Responsibilities II01:23

Nurses' Legal Responsibilities II

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Establishing a secure, collaborative nurse-patient relationship is crucial for delivering high-quality care. This relationship, founded on trust, respect, and honesty, enhances the patient's comfort and willingness to share vital health information. For example, a nurse who listens actively and without judgment provides clear information about health conditions and treatment options and respects patient decisions, which builds a trusting relationship.
Communication between nurses and...
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The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
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The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress

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Primum Non Nocere.

Hans Van Rostenberghe1

  • 1Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

The Malaysian Journal of Medical Sciences : MJMS
|March 8, 2021
PubMed
Summary

Two new mRNA COVID-19 vaccines are available, but long-term safety data is limited. Experts debate mass vaccination due to unknown effects of messenger RNA (mRNA) and potential for enhanced disease severity.

Area of Science:

  • Immunology
  • Vaccinology
  • Public Health

Background:

  • The COVID-19 pandemic presents a severe global health crisis.
  • Biotechnology firms have rapidly developed vaccines, with two mRNA vaccines receiving emergency use authorization.
  • Messenger RNA (mRNA) vaccine technology is novel and lacks extensive human testing.

Purpose of the Study:

  • To evaluate the current status of mRNA COVID-19 vaccines.
  • To discuss the implications of limited long-term safety data for mass vaccination campaigns.
  • To highlight expert concerns regarding novel vaccine technologies.

Main Methods:

  • Review of current scientific literature on mRNA vaccine technology.
  • Analysis of emergency use authorization data for COVID-19 vaccines.
Keywords:
COVID-19mRNAsafetyside effectsvaccine

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  • Discussion of expert opinions on vaccine safety and efficacy.

    • Main Results:

    • Two mRNA vaccines have been authorized for emergency use globally.
    • Significant gaps exist in medium- and long-term safety data for mRNA vaccines.
    • Concerns include potential long-term cellular effects and vaccine-enhanced disease severity.

    Conclusions:

    • The rapid deployment of mRNA vaccines necessitates careful consideration of unknown risks.
    • Further research is crucial to address uncertainties surrounding mRNA vaccine safety and long-term effects.
    • Balancing the benefits of vaccination with potential risks requires ongoing scientific and public health dialogue.