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Usual interstitial pneumonia progressing to nonspecific interstitial pneumonia-like pattern on high-resolution CT

Kai Yazaki^1,2, Mizu Nonaka^1,2, Rie Shigemasa^1,2

¹Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Tokai, Japan.

Radiology Case Reports

|March 8, 2021

Abstract:

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease. Although high-resolution computed tomography (HRCT) is important for the diagnosis of IPF, the changes in the HRCT findings in IPF are not fully understood. The patient was a 66-year-old man. His HRCT findings had atypically developed from a probable usual interstitial pneumonia pattern to a nonspecific interstitial pneumonia (NSIP) like pattern over 6 years. On the basis of the histologic examination and multidisciplinary discussion, IPF was diagnosed, and nintedanib, administered. This case can be useful for the differential diagnosis of IPF and NSIP.

Keywords:

Computed tomography Idiopathic pulmonary fibrosis Nonspecific interstitial pneumonia Usual interstitial pneumonia

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