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Updated: Nov 15, 2025

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
Published on: March 15, 2024
Kyle R Eberlin1, Brent B Pickrell1, Ryoko Hamaguchi2
1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Diffuse nerve injuries from crush trauma present surgical challenges. A "reset neurectomy" technique, involving proximal neurectomy and immediate repair, offers a potential solution for neuropathic pain.
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