Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

630
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
630

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Base editing reveals an essential role for NANOG in human embryogenesis.

Nature·2026
Same author

Modeling human embryo implantation in vitro.

Cell·2025
Same author

NMN supplementation as a strategy to improve oocyte quality: a systematic review and transcriptomic analysis.

Journal of assisted reproduction and genetics·2025
Same author

Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling.

Developmental cell·2024
Same author

Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells.

Development (Cambridge, England)·2024
Same author

The Effect of Progesterone Elevation on the Day of Trigger Administration: A Review of the Literature.

Journal of reproduction & infertility·2024

Related Experiment Video

Updated: Nov 15, 2025

Vitrification of In Vitro Matured Oocytes Collected from Adult and Prepubertal Ovaries in Sheep
06:53

Vitrification of In Vitro Matured Oocytes Collected from Adult and Prepubertal Ovaries in Sheep

Published on: July 10, 2021

5.4K

The First Livebirth Using Warmed Oocytes by a Semi-Automated Vitrification Procedure.

Xavier Orriols Brunetti1, Suzanne Cawood1, Matthew Gaunt1

  • 1- The Centre for Reproductive and Genetic Health, London, United Kingdom.

Journal of Reproduction & Infertility
|March 8, 2021
PubMed
Summary

The GAVI™ system offers a semi-automated approach to oocyte vitrification, improving upon manual methods. This case report details a successful livebirth using this technology, highlighting its potential for standardized and safer fertility treatments.

Keywords:
CryopreservationGAVITMOocytesPGT-ASemi-automated vitrification systemVitrification

More Related Videos

Minimum Volume Vitrification of Immature Feline Oocytes
07:16

Minimum Volume Vitrification of Immature Feline Oocytes

Published on: June 24, 2020

6.8K
Author Spotlight: Advancing Fertility Preservation in Young Female Cancer Patients Through Ovarian Tissue Vitrification and In Vitro Follicular Growth
05:53

Author Spotlight: Advancing Fertility Preservation in Young Female Cancer Patients Through Ovarian Tissue Vitrification and In Vitro Follicular Growth

Published on: August 9, 2024

1.6K

Related Experiment Videos

Last Updated: Nov 15, 2025

Vitrification of In Vitro Matured Oocytes Collected from Adult and Prepubertal Ovaries in Sheep
06:53

Vitrification of In Vitro Matured Oocytes Collected from Adult and Prepubertal Ovaries in Sheep

Published on: July 10, 2021

5.4K
Minimum Volume Vitrification of Immature Feline Oocytes
07:16

Minimum Volume Vitrification of Immature Feline Oocytes

Published on: June 24, 2020

6.8K
Author Spotlight: Advancing Fertility Preservation in Young Female Cancer Patients Through Ovarian Tissue Vitrification and In Vitro Follicular Growth
05:53

Author Spotlight: Advancing Fertility Preservation in Young Female Cancer Patients Through Ovarian Tissue Vitrification and In Vitro Follicular Growth

Published on: August 9, 2024

1.6K

Area of Science:

  • Reproductive medicine and assisted reproductive technologies (ART).
  • Cryobiology and gamete preservation.

Background:

  • Manual oocyte vitrification is prone to errors and variability.
  • The GAVI™ system introduces semi-automation to oocyte vitrification, aiming for standardization.
  • Oocyte cryopreservation is a critical component of modern fertility treatments.

Observation:

  • Donor oocytes were vitrified using the GAVI™ system and stored.
  • Oocytes were warmed, inseminated, and embryos cultured to blastocyst stage.
  • Embryos underwent PGT-A (preimplantation genetic testing for aneuploidy) via next-generation sequencing.
  • A single euploid embryo transfer resulted in a healthy livebirth for a 42-year-old patient.

Findings:

  • The GAVI™ system facilitated the vitrification and subsequent successful warming of oocytes.
  • The process led to the creation and transfer of a euploid blastocyst.
  • A healthy livebirth was achieved, demonstrating the viability of the oocytes preserved with the GAVI™ system.

Implications:

  • Semi-automated vitrification systems like GAVI™ have the potential to standardize global laboratory procedures.
  • This technology may reduce risks associated with manual oocyte vitrification.
  • Further randomized studies are necessary to confirm the safety and efficacy of the GAVI™ system for widespread adoption.