Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olfaction01:25

Olfaction

46.9K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
46.9K
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

10.8K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
10.8K
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

10.4K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
10.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Music-Inspired Acoustic-Piezoelectric Stimulation Accelerates Extracellular Vesicle Production and Programs Therapeutic Function.

Acta biomaterialia·2026
Same author

Targeting neurodevelopmental miR132-3p promotes neuroprotection and axon regeneration after optic nerve injury in mice.

Brain research·2026
Same author

Silver-Functionalized Metal Oxide Nanofibers for High Precision Chlorine Sensing at the Parts-Per-Billion Scale with Tunable Selectivity.

ACS sensors·2026
Same author

Energy Barrier Modulation vs Kinetic Acceleration: Tailoring WO<sub>3</sub> Nanofibers for Trace-Level Mustard Gas Simulant Detection.

ACS sensors·2026
Same author

Structural and Electronic Engineering of WSe<sub>2</sub> for High-Performance Gas Sensing.

ACS sensors·2026
Same author

Vacuolar ATPase subunit Atp6v0c transgene promotes neuroprotection and long-distance axon regeneration in injured retinal ganglion neurons.

Molecular therapy. Nucleic acids·2026
Same journal

An integrated annotation strategy for the phytochemical characterization of Xie-Bai-San decoction based on UPLC-Q Exactive Orbitrap HRMS, multi-database screening, and feature-based molecular networking.

Frontiers in chemistry·2026
Same journal

Core-shell structured nanomaterials in dual-modal magnetic resonance imaging guided antitumor effect via combined treatment.

Frontiers in chemistry·2026
Same journal

Photo-responsive nanozymes: from photocatalytic mechanisms to precision therapy.

Frontiers in chemistry·2026
Same journal

From theoretical energy to practical utilization: interfacial stability, transport kinetics, and cell-level design in high-energy lithium-metal batteries.

Frontiers in chemistry·2026
Same journal

Zinc-vacancy defects in ZnO nanorods induced visible-light activity of photoelectrochemical glucose sensing: experimental and DFT+U analysis.

Frontiers in chemistry·2026
Same journal

Integrating multi-isotope calibration and infrared-assisted digestion for robust and sustainable multielemental determination in agroalimentary matrices by ICP-MS.

Frontiers in chemistry·2026
See all related articles

Related Experiment Video

Updated: Nov 14, 2025

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
15:04

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

Published on: May 20, 2016

11.2K

Nanoengineering Approaches Toward Artificial Nose.

Sanggon Kim1, Jacob Brady1, Faraj Al-Badani1

  • 1Department of Chemical and Environmental Engineering, University of California-Riverside, Riverside, CA, United States.

Frontiers in Chemistry
|March 8, 2021
PubMed
Summary
This summary is machine-generated.

Researchers are developing advanced artificial noses using nanoengineered materials to improve gas detection. These artificial noses aim to surpass human olfactory capabilities through enhanced sensitivity and selectivity in gas sensors.

Keywords:
artificial noseelectrical sensor arrayelectronic nosegas sensornanomaterialsoptical sensoroptoelectrical sensor

More Related Videos

Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization
06:00

Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization

Published on: August 27, 2021

5.7K
Enhancement Method of Surface Acoustic Wave-Atomizer Efficiency for Olfactory Display
08:06

Enhancement Method of Surface Acoustic Wave-Atomizer Efficiency for Olfactory Display

Published on: November 14, 2018

8.3K

Related Experiment Videos

Last Updated: Nov 14, 2025

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
15:04

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

Published on: May 20, 2016

11.2K
Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization
06:00

Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization

Published on: August 27, 2021

5.7K
Enhancement Method of Surface Acoustic Wave-Atomizer Efficiency for Olfactory Display
08:06

Enhancement Method of Surface Acoustic Wave-Atomizer Efficiency for Olfactory Display

Published on: November 14, 2018

8.3K

Area of Science:

  • Nanomaterials Science
  • Chemical Sensing Technology
  • Artificial Olfaction

Background:

  • Extensive research has focused on creating artificial noses using gas sensor arrays to mimic or exceed mammalian olfaction.
  • Nanoengineered materials offer advantages over micro/macroscale materials, addressing limitations in sensitivity and selectivity for chemical sensors.

Purpose of the Study:

  • To review fundamental gas sensing mechanisms across different material classes and sensing modalities (electrical, optical, optoelectronic).
  • To survey strategies for nanoengineering and functionalizing materials to enhance gas sensing performance, particularly sensitivity and selectivity.

Main Methods:

  • Review of nanoengineered materials including semiconducting metal oxides, transition metal dichalcogenides, carbonaceous nanomaterials, and conducting polymers for electrical sensing.
  • Discussion of nano-enabled techniques for optical gas detection, such as photonic crystals, surface plasmonic sensing, and nanoscale waveguides.
  • Exploration of optoelectrical sensing as an emerging modality.

Main Results:

  • Nanoengineering significantly improves sensitivity and selectivity of gas sensors compared to traditional materials.
  • Various strategies exist for tailoring nanomaterials to achieve desired cross-sensitivity and selectivity for artificial nose applications.
  • Optical and electrical sensing modalities show promise, with optoelectrical sensing identified as a key area for future research.

Conclusions:

  • Nanoengineered materials are crucial for advancing artificial nose technology, offering superior performance in gas detection.
  • Continued focus on material engineering and exploring novel sensing modalities like optoelectrical sensing will drive future developments in artificial olfaction.