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Updated: Nov 14, 2025
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Corneal Donor Tissue Preparation for Endothelial Keratoplasty
Published on: June 12, 2012
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Penetrating keratoplasty using collagen crosslinked donor tissue: A case report
1Massachusetts Eye and Ear Infirmary Boston, USA.
American Journal of Ophthalmology Case Reports
|March 8, 2021
Summary
Pretreatment with corneal crosslinking (CXL) of donor tissue protected a phthisical eye after penetrating keratoplasty (PKP). This novel approach prevented corneal melt and preserved corneal structure for 8 years.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Tissue Engineering
Background:
- Corneal melt and graft failure are significant complications following Boston keratoprosthesis (K-Pro I) implantation.
- Penetrating keratoplasty (PKP) is an alternative, but carries risks of graft failure and keratolysis, especially in compromised eyes.
