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Related Experiment Video

Updated: Nov 14, 2025

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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HaNDL with bilateral central venous occlusions.

Wendy Wang1, Heather G Mack2, Richard Stawell3

  • 1Neurology, Alfred Hospital, Melbourne, Victoria, Australia.

BMJ Neurology Open
|March 8, 2021
PubMed
Summary
This summary is machine-generated.

Headache and focal Neurological Deficits with cerebrospinal fluid Lymphocytosis (HaNDL) syndrome, typically self-limited, can present with rare neuro-ophthalmic complications like retinal vein occlusions. Early recognition is key for managing this condition.

Keywords:
headacheneuroophthalmologyvision

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Area of Science:

  • Neuro-ophthalmology
  • Neurology
  • Vascular Neurology

Background:

  • Headache and focal Neurological Deficits with cerebrospinal fluid Lymphocytosis (HaNDL) is a rare, idiopathic, and self-limited neurological disorder.
  • This condition typically involves temporary neurological deficits and headache, often accompanied by cerebrospinal fluid lymphocytosis.

Purpose of the Study:

  • To report a unique case of HaNDL syndrome with unusual neuro-ophthalmic manifestations.
  • To highlight the importance of recognizing potential ocular complications in HaNDL syndrome.

Main Methods:

  • Case presentation of a patient diagnosed with HaNDL syndrome.
  • Detailed examination of unique findings, including bilateral central retinal vein occlusions and optic disc hemorrhages.

Main Results:

  • The patient exhibited florid optic disc hemorrhages secondary to bilateral central retinal vein occlusions.
  • The patient experienced a complete recovery following conservative management.

Conclusions:

  • HaNDL syndrome can be associated with significant neuro-ophthalmic complications, such as retinal vascular events.
  • Medical professionals should be vigilant for these complications to ensure comprehensive patient care.