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Detection of Copy Number Alterations Using Single Cell Sequencing
Published on: February 17, 2017
A comprehensive list of cloned human DNA sequences
1Institut für Humangenetik, Universität Göttingen, FRG.
Nucleic Acids Research
|January 1, 1988
Summary
This study presents a comprehensive list of cloned DNA sequences from the human genome, serving as a guide to available gene and pseudogene clones, uncharacterized DNA, and repetitive elements.
Area of Science:
- Genomics
- Molecular Biology
- Bioinformatics
Background:
- The human genome contains a vast array of DNA sequences, including genes, pseudogenes, and repetitive elements.
- Access to well-characterized DNA clones is crucial for various research applications, including gene function studies and disease research.
- Previous efforts to catalog cloned human DNA sequences have been fragmented, necessitating a consolidated resource.
Purpose of the Study:
- To compile a comprehensive and accessible guide to available cloned DNA sequences from the human genome.
- To facilitate researchers' access to specific gene, pseudogene, uncharacterized DNA segments, and repetitive DNA element clones.
- To serve as a reference for clone availability and support future genomic research.
Main Methods:
- Systematic literature review of published reports detailing cloned human DNA sequences.
- Inclusion criteria focused on cDNA, genomic, and synthetic clones.
- Categorization of clones based on sequence type: gene, pseudogene, uncharacterized DNA, and repetitive DNA elements.
Main Results:
- A curated list of published human DNA sequences available as clones has been compiled.
- The list encompasses a diverse range of sequence types, including coding (cDNA), non-coding (genomic), and synthetic constructs.
- Specific entries detail clones representing genes, pseudogenes, uncharacterized DNA segments, and repetitive DNA elements.
Conclusions:
- The presented list provides a valuable resource for researchers seeking specific human DNA clones.
- This guide enhances the discoverability and availability of critical genomic research tools.
- Facilitating access to these clones will accelerate research in human genetics, molecular biology, and medicine.
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