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Updated: Nov 14, 2025

Transcutaneous Microcirculatory Imaging in Preterm Neonates
06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

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Transcutaneous Bilirubin Levels and Risk of Significant Hyperbilirubinemia in Early-Term and Term Newborns

Serdar Umit Sarici, Murat Ozcan, Melis Akpinar

    Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN
    |March 8, 2021
    PubMed

    Insights

    Early-term newborns have higher transcutaneous bilirubin (TcB) levels and an increased risk of jaundice requiring treatment compared to full-term infants. Close monitoring for pathologic jaundice is recommended for these infants.

    Area of Science:

    • Neonatal Medicine
    • Pediatrics
    • Public Health

    Background:

    • Neonatal jaundice is a common condition.
    • Early-term birth (37 0/7 to 38 6/7 weeks) is increasingly recognized.
    • The bilirubin course in early-term infants compared to term infants is not well-defined.

    Purpose of the Study:

    • To compare transcutaneous bilirubin (TcB) levels in early-term and term newborns during the first month of life.
    • To assess the risk of significant hyperbilirubinemia requiring treatment in early-term newborns.

    Main Methods:

    • Prospective, controlled cohort study.
    • Included 400 early-term and 320 term newborns.
    • Six longitudinal transcutaneous bilirubin measurements were performed up to 30 days post-birth.

    Main Results:

    • Early-term newborns exhibited significantly higher TcB values at all measurement points (p < .001).
    • Early-term infants had a nearly twofold increased risk of jaundice requiring treatment (RR = 1.91, p = .0046).
    • TcB levels peaked around 96 hours post-birth and gradually decreased by day 30 in both groups.

    Conclusions:

    • Early-term newborns demonstrate higher TcB levels than term newborns.
    • These infants face an elevated risk of significant hyperbilirubinemia.
    • Close monitoring for pathologic jaundice and potential phototherapy is crucial for early-term infants.
    Abstract

    Keywords:
    early-term newbornneonatal hyperbilirubinemianeonatal jaundicesignificant hyperbilirubinemiaterm newborntranscutaneous bilirubinometry

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