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Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
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NMR magnets for portable applications using 3D printed materials.

Belal M K Alnajjar1, André Buchau1, Lars Baumgärtner1

  • 1University of Stuttgart, Institute of Smart Sensors, Pfaffenwaldring 47, 70569 Stuttgart, Germany.

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|March 8, 2021
PubMed
Summary

3D printing with steel-filled filament enables lightweight, high-precision NMR magnets. This cost-effective method allows for custom components, paving the way for portable NMR applications.

Keywords:
3D printingAdditive manufacturingMobile NMRNMR magnetPermanent magnet designPrinted materialsShimming

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Area of Science:

  • Materials Science
  • Magnetic Resonance Imaging
  • Additive Manufacturing

Background:

  • Conventional NMR magnets often rely on heavy iron components, limiting portability.
  • Developing lightweight, high-precision magnetic components is crucial for advancing portable NMR technology.

Purpose of the Study:

  • To explore the use of 3D printing with steel-filled filament for fabricating NMR magnet components.
  • To demonstrate the feasibility of creating lightweight, high-performance NMR magnets for portable applications.

Main Methods:

  • Utilized a commercially available steel-particle-filled filament for 3D printing NMR magnet components.
  • Designed and fabricated two H-shaped NMR magnets: one with a 3D-printed yoke and another with 3D-printed passive shim structures.
  • Employed numerical optimization using non-uniform rational basis splines (NURBS) for component geometry.

Main Results:

  • Successfully printed critical NMR magnet components, including pole pieces, flux-conducting yokes, and arbitrarily shaped shim structures.
  • Achieved significant potential weight reduction by replacing conventional iron yokes with 3D-printed alternatives.
  • Measured NMR spectral line widths of 54 ppm and 250 ppm for the two fabricated magnets, demonstrating high performance.

Conclusions:

  • 3D printing with steel-filled filament offers a versatile, robust, and inexpensive method for realizing high-performance NMR magnets.
  • The proposed approach facilitates the development of lightweight NMR magnets suitable for portable applications.
  • The demonstrated design and optimization strategy highlights the efficiency of additive manufacturing in magnetic resonance.