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The prevalence of depression in Iranian children: A systematic review and meta-analysis
Leily Mahmudi1, Parvaneh Karimi2, Fatemeh Sadat Arghavan3
1Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
Insights
Depression is highly prevalent in Iranian children, affecting 42.3% of those studied. This meta-analysis highlights a significant difference compared to global estimates, underscoring the need for targeted interventions for child mental health.
Area of Science:
- Pediatric Mental Health
- Epidemiology
- Psychiatry
Background:
- Childhood depression is a growing concern globally.
- Understanding the prevalence of depression in specific populations, like Iranian children, is crucial for public health initiatives.
Purpose of the Study:
- To evaluate the prevalence of depression among children in Iran.
- To compare depression rates in Iranian children with global estimates.
- To identify potential factors influencing depression prevalence in this demographic.
Main Methods:
- A comprehensive meta-analysis was conducted, adhering to MOOSE protocol and PRISMA guidelines.
- Extensive literature searches were performed across international and Iranian databases until April 2020.
- Data from 34 studies involving 23,779 Iranian children were synthesized.
Main Results:
- The overall prevalence of depression in Iranian children was found to be 42.3%.
- Depression was more prevalent in girls (42.1%) than in boys (29.6%), with a significant odds ratio of 1.33 for females.
- Prevalence varied across severity levels: mild (20.3%), moderate (15.0%), major (14.5%), and deep (4.3%). Subgroup analyses indicated significant variations based on province and school grade.
Conclusions:
- Depression is a common condition among Iranian children, with prevalence rates exceeding global averages.
- The findings underscore the urgent need for early identification and effective treatment strategies for childhood depression in Iran.
- Further research and public health interventions are warranted to address this significant mental health challenge.
Introduction:
The present study was conducted to evaluate the prevalence of depression in Iranian children.
Method:
This meta-analysis was registered in PROSPERO with code (CRD42020216632) and performed based on the MOOSE protocol and PRISMA guidelines. Title and abstract of articles were searched without time limit until April 2020 in international databases PubMed/Medline, Scopus, Embase, Science Direct, Cochrane Library, CINAHL, EBSCO, Web of Science, Google Scholar, and Iranian databases.
Results:
In 34 studies with a sample size of 23,779 Iranian children, the prevalence of depression was estimated 42.3 % (95 %CI: 34.9-50.0). Prevalence of depression in girls in 20 studies with a sample size of 11,170 was estimated 42.1 % (95 %CI: 32.7-52.1) and the prevalence of depression in males in 20 studies with a sample size of 4678 was estimated 29.6 % (95 %CI: 21.2-39.7). The odds ratio of female to male depression was 1.33 (95 %CI: 1.07-1.65, P < 0.011). Prevalence of mild, moderate, major and deep depression was 20.3 % (95 %CI: 16.4-24.9), 15.0 % (95 %CI: 11.3-19.7), 14.5 % (95 %CI: 10.8-19.1), and 4.3 % (95 %CI: 1.8-9.8), respectively. In subgroup analysis for prevalence of depression in Iranian children, the variables of geographical area (P = 0.258), quality of studies (P = 0.186), type of questionnaire (P = 0.907), sample size (P = 0.500) and year of studies (P = 0.538) were not significant, but subgroup analysis of province (P < 0.001) and school grade (P < 0.001) were significant.
Conclusion:
The results of the present meta-analysis showed that depression is common in Iranian children and is much higher than global estimates. These findings emphasize the importance of identifying and providing treatment to children who are most in need.
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