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Published on: August 17, 2022
[Expert consensus of perioperative management in pediatric liver transplantation]
Insights
This consensus provides evidence-based guidelines for pediatric liver transplantation (PLT) to improve outcomes. It addresses preoperative, intraoperative, and postoperative care to reduce complications and enhance recovery for children undergoing PLT.
Area of Science:
- Pediatric Surgery
- Hepatology
- Transplantation Medicine
Background:
- Pediatric liver transplantation (PLT) is a vital treatment for pediatric end-stage liver and metabolic diseases.
- Despite successful application, PLT center development is uneven, lacking industry-wide standards.
- Variations in care impact post-transplant outcomes and quality of life for children.
Purpose of the Study:
- To establish a consensus on perioperative care for pediatric liver transplantation (PLT).
- To provide evidence-based recommendations to standardize PLT practices nationwide.
- To improve post-operative recovery and long-term quality of life for pediatric recipients.
Main Methods:
- Multidisciplinary expert committee convened to review domestic and international research.
- Formulated a perioperative consensus based on evidence-based medicine principles.
- Recommendations cover preoperative assessment, intraoperative management, and postoperative care.
Main Results:
- A comprehensive perioperative consensus for pediatric liver transplantation (PLT) was developed.
- Guidelines address key stages: preoperative preparation, intraoperative management, and postoperative care.
- The consensus aims to standardize care and reduce post-operative complications.
Conclusions:
- This consensus offers crucial guidelines for centers performing or preparing for pediatric liver transplantation (PLT).
- Standardized perioperative care is essential for optimizing outcomes in pediatric liver transplant recipients.
- Implementation of these recommendations can enhance recovery and improve the quality of life for children.
Abstract:
Pediatric liver transplantation (PLT) is an effective strategy of treating various acute or chronic end-stage liver diseases and inherited metabolic diseases in children.PLT has been applied in many transplant centers nationwide and has achieved satisfactory results.However,the development of transplant centers is uneven,and there is a lack of consensus and standards within the industry.In order to reduce post-operative complications,accelerate post-operative recovery,and improve the short-and long-term quality of life of children,the Enhanced Recovery After Surgery Committee of Chinese Research Hospital Association organized multidisciplinary experts to summarize the progress of domestic and international research,and formulated a perioperative consensus on PLT based on the principles of evidence-based medicine.The consensus provides recommendations for perioperative PLT from three aspects:preoperative assessment and preparation,intraoperative management and postoperative management,in order to provide reference guidelines for centers that are conducting or preparing to conduct PLT.

