Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Corrigendum to "Cell Sheet Technology-Driven Re-epithelialization and Neovascularization of Skin Wounds" [Acta Biomaterialia (2014) 3145-3155].

Acta biomaterialia·2026

Same author

"Cayenne pepper" rash - A case of Schamberg disease.

Semergen·2026

Same author

A bio-behavioral model of systemic inflammation at breast cancer diagnosis and fatigue of clinical importance 2 years later.

Annals of oncology : official journal of the European Society for Medical Oncology·2024

Same author

Correction: Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65.

Gene therapy·2024

Same author

Reports on vascular catheter-associated thromboembolic events in a burn unit - a gap in the literature?

Acta chirurgiae plasticae·2024

Same author

The Silent Threat-Alkali Foot Burn: A Case Report.

Annals of burns and fire disasters·2024

Same journal

Large urethral false passage during a routine catheterization - low threshold for better outcome.

Acta chirurgiae plasticae·2026

Same journal

Post-otoplasty keloid scars - treatment strategies and case reports.

Acta chirurgiae plasticae·2026

Same journal

Extensive keloid scar of the left auricle - combined treatment of excision followed by brachytherapy: a case report.

Acta chirurgiae plasticae·2026

Same journal

Digital retractile keloid in a context of spontaneous keloids - a case report.

Acta chirurgiae plasticae·2026

Same journal

Intraoperative cone beam computed tomography in craniomaxillofacial traumatology - a case report.

Acta chirurgiae plasticae·2026

Same journal

Taylor's flap reconstruction following abdominoperineal resection for advanced hidradenitis suppurativa - a case series and literature review.

Acta chirurgiae plasticae·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 14, 2025

Engineered Vascularized Muscle Flap

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

TISSUE ENGINEERING IN PLASTIC SURGERY - WHAT HAS BEEN DONE.

J Ribeiro, R P Pirraco, R Horta

Acta Chirurgiae Plasticae

|March 9, 2021

Summary

This summary is machine-generated.

Tissue engineering uses engineering and life sciences to create functional biologic substitutes for reconstructive surgery. While promising, widespread clinical application requires further long-term studies to address current limitations.

Keywords:

Basal cell carcinoma Bioengineering Regeneration Stem cells Tissue engineering plastic surgery reconstructive surgery regeneration stem cells

More Related Videos

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Related Experiment Videos

Last Updated: Nov 14, 2025

Engineered Vascularized Muscle Flap

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Area of Science:

Biomedical Engineering
Regenerative Medicine

Background:

Tissue engineering merges engineering and life sciences to develop functional biologic substitutes.
Plastic surgeons play a vital role in the research and clinical application of engineered tissues for reconstructive surgery.

Purpose of the Study:

To summarize tissue engineering principles.
To review current applications, breakthroughs, limitations, and future directions in tissue engineering.
To cover tissue engineering in skin, craniofacial, musculoskeletal, nerve, vascular, and adipose tissue applications.

Main Methods:

This study is a narrative review.
Literature search on tissue engineering principles, applications, and future prospects.

Main Results:

Tissue engineering research is rapidly expanding with several engineered constructs available.
Clinical application of engineered tissues is still limited and requires further investigation.

Conclusions:

Tissue engineering holds significant promise for regenerative medicine and reconstructive surgery.
Further long-term studies are essential to overcome current limitations and enable widespread clinical adoption.