Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anatomical Positions01:11

Anatomical Positions

17.6K
In anatomy, several standard anatomical positions are used as references for describing the position and orientation of different body parts. These positions help provide a common frame of reference when discussing anatomical structures. The anatomical position is the standard reference point for describing the body's position and orientation. In this position:
The body is upright, facing forward, and standing erect.
The feet are parallel and flat on the floor.
The arms are hanging by the...
17.6K
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

1.1K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
1.1K
Insulin Formulations: Types and Delivery01:27

Insulin Formulations: Types and Delivery

387
Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into...
387
Assessing Body Temperature - Axilla01:14

Assessing Body Temperature - Axilla

912
Procedural Guide for Assessing Axillary Body Temperature using a Digital Thermometer:
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
912
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

395
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
395
Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

687
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
687

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethical Implementation of Organ Donation Following Medical Assistance in Dying: Recommendations of the Ethics Committee of the Transplantation Society.

Transplantation·2026
Same author

Apnea Testing for Brain Death/Death by Neurologic Criteria in Adults: A Prospective Multicenter Observational Study Assessing the Relationship Between Methodology, Safety, and Duration.

Critical care explorations·2026
Same author

Correction: Safety and outcomes of laparoscopic bile duct exploration: a UK-wide multi-centre study (R-ALiCE).

Surgical endoscopy·2026
Same author

The Military Health System Data Repository: Leveraging Closed, Familial-Linked Electronic Health Record Data for a Large Generalizable US Population.

Pharmacoepidemiology and drug safety·2026
Same author

Correction to: Safety and outcomes of laparoscopic bile duct exploration: a UK-wide multi-centre study (R-ALiCE).

Surgical endoscopy·2026
Same author

Commentary on The Dante Project and The Gates of Hell: The Anatomy of Movement.

Academic medicine : journal of the Association of American Medical Colleges·2026

Related Experiment Video

Updated: Nov 14, 2025

Ultrasound-guided Transthoracic Intramyocardial Injection in Mice
08:22

Ultrasound-guided Transthoracic Intramyocardial Injection in Mice

Published on: August 5, 2014

15.4K

Ideal body position for epinephrine autoinjector administration.

Qing Wang1, Luke Pittman2, Andrew Healey3

  • 1From the Department of Medicine, Madigan Army Medical Center, Tacoma, Washington.

Allergy and Asthma Proceedings
|March 9, 2021
PubMed
Summary

Body position does not significantly alter subcutaneous tissue depth for epinephrine autoinjector administration. Prompt epinephrine delivery is recommended for anaphylaxis, regardless of patient position.

More Related Videos

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
14:24

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

Published on: January 21, 2018

11.9K
Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction
06:47

Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction

Published on: July 25, 2025

260

Related Experiment Videos

Last Updated: Nov 14, 2025

Ultrasound-guided Transthoracic Intramyocardial Injection in Mice
08:22

Ultrasound-guided Transthoracic Intramyocardial Injection in Mice

Published on: August 5, 2014

15.4K
Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
14:24

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

Published on: January 21, 2018

11.9K
Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction
06:47

Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction

Published on: July 25, 2025

260

Area of Science:

  • Emergency Medicine
  • Pharmacology
  • Anatomy

Background:

  • Epinephrine is the primary treatment for anaphylaxis.
  • Intramuscular (IM) injection is more effective than subcutaneous (SC) for epinephrine delivery.
  • Optimal body positioning for epinephrine autoinjector (EAI) use is not established.

Purpose of the Study:

  • To determine if body position affects subcutaneous tissue depth (SCTD).
  • To assess the impact of body position on potential EAI delivery into the IM space.

Main Methods:

  • Adult volunteers had their vastus lateralis SCTD measured using ultrasound.
  • Measurements were taken in standing, sitting, and supine positions.
  • Data on age, sex, and BMI were collected and analyzed.

Main Results:

  • No significant difference in SCTD was found across standing, sitting, and supine positions.
  • Women exhibited significantly greater SCTD than men (2.72 cm vs. 1.10 cm).
  • Body mass index (BMI) did not correlate significantly with SCTD.

Conclusions:

  • Body position does not appear to significantly alter the skin-to-muscle distance in the thigh.
  • There may not be an ideal body position for EAI administration.
  • Prompt epinephrine administration during anaphylaxis is advised in any position.