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Updated: Nov 14, 2025

Designing a Bio-responsive Robot from DNA Origami
Published on: July 8, 2013
Homological scaffold via minimal homology bases
Marco Guerra1, Alessandro De Gregorio2, Ulderico Fugacci3
1Politecnico di Torino, Department of Mathematical Sciences, Torino, Italy. marco_guerra@polito.it.
Abstract:
The homological scaffold leverages persistent homology to construct a topologically sound summary of a weighted network. However, its crucial dependency on the choice of representative cycles hinders the ability to trace back global features onto individual network components, unless one provides a principled way to make such a choice. In this paper, we apply recent advances in the computation of minimal homology bases to introduce a quasi-canonical version of the scaffold, called minimal, and employ it to analyze data both real and in silico. At the same time, we verify that, statistically, the standard scaffold is a good proxy of the minimal one for sufficiently complex networks.
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