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Updated: Nov 14, 2025

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Three-Component Self-Assembly Changes its Course: A Leap from Simple Polymers to 3D Networks of Spherical Host-Guest
Eugenia Peresypkina1, Kevin Grill1, Barbara Hiltl1
1Institute of Inorganic Chemistry, University of Regensburg, 93040, Regensburg, Germany.
Abstract:
One-pot self-assembly reactions of the polyphosphorus complex [Cp*Fe(η5 -P5 )] (A), a coinage metal salt AgSbF6 , and flexible aliphatic dinitriles NC(CH2 )x CN (x=1-10) yield 1D, 2D, and 3D coordination polymers. The seven-membered backbone of the dinitrile was experimentally found as the borderline for the self-assembly system furnishing products of different kinds. At x<7, various rather simple polymers are exclusively formed possessing either 0D or 1D Ag/A structural motifs connected by dinitrile spacers, while at x≥7, the self-assembly switches to unprecedented extraordinary 3D networks of nano-sized host-guest assemblies (SbF6 )@[(A)9 Ag11 ]11+ (x=7) or (A)@[(A)12 Ag12 ]12+ (x=8-10) linked by dinitriles. The polycationic nodes represent the first superspheres based on A and silver and are host-guest able. All products are characterized by NMR spectroscopy, mass spectrometry, and single-crystal X-ray diffraction. The assemblies [(A)12 Ag12 ]12+ were visualized by transmission electron microscopy.
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