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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Nonpharmacological Interventions for Pediatric Migraine: A Network Meta-analysis
Helen Koechlin1,2,3, Joe Kossowsky1,2,3, Thanh Lan Lam4
1Division of Clinical Psychology and Psychotherapy, University of Basel, Basel, Switzerland.
Pediatrics
|March 10, 2021
Summary
Nonpharmacological treatments for pediatric migraine, including self-administered therapies and biofeedback, show effectiveness compared to waiting lists. However, individual interventions lacked statistical power in this review of pediatric migraine treatments.
Area of Science:
- Neurology
- Pediatrics
- Evidence-based medicine
Background:
- Migraine is a prevalent neurological disorder affecting children and adolescents.
- A comprehensive comparison of various nonpharmacological treatment options for pediatric migraine is currently lacking.
Purpose of the Study:
- To evaluate the efficacy of nonpharmacological treatments for pediatric migraine.
- To compare the effectiveness of different nonpharmacological interventions against a waiting list control group.
Main Methods:
- A systematic review and network meta-analysis was conducted.
- Included randomized controlled trials (RCTs) of nonpharmacological treatments for episodic migraine in pediatric populations.
- Data from Medline, Cochrane, Embase, and PsycINFO databases were analyzed up to August 5, 2019.
Main Results:
- Twelve studies with 576 participants were included in the analysis.
- Grouped interventions (self-administered, biofeedback, relaxation, psychological treatments, and placebos) demonstrated significantly greater efficacy than waiting lists.
- Effect sizes (SMD) ranged from 1.14 to 1.44, indicating moderate to large effects.
- Individual interventions did not reach statistical significance compared to waiting lists, likely due to limited statistical power.
Conclusions:
- Components of nonpharmacological interventions are effective for treating pediatric migraine.
- Findings suggest that certain nonpharmacological approaches offer benefits for young migraine sufferers.
- Further large-scale, multicentered research is recommended to identify factors influencing individual treatment responses.
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