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Updated: Nov 14, 2025

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
Published on: January 10, 2019
[Optical coherence tomography biomarkers in epimacular membranes and vitreomacular traction syndrome]
C Haritoglou1, J P Hubschman2, R G Schumann3
1Augenklinik Herzog Carl Theodor, Nymphenburger Str. 43, 80335, München, Deutschland. Christos.haritoglou@med.uni-muenchen.de.
Abstract:
Using high-resolution imaging, such as optical coherence tomography (OCT), the different layers of the retina as well as the vitreoretinal interface and its alterations can be very clearly differentiated. This includes the morphological characteristics of tractive maculopathies, such as epiretinal gliosis and vitreomacular traction syndrome. Additionally, structural alterations of the various layers of the neurosensory retina as a result of traction due to these pathologies can be demarcated. The latter have been investigated in clinical trials and evaluated as OCT biomarkers with respect to their prognostic and predictive value. In this review we would like to present and discuss various OCT biomarkers in the context of epimacular membranes and vitreomacular traction syndrome.

