Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

656
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
656
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

928
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
928
High-Resolution Mass Spectrometry (HRMS)01:15

High-Resolution Mass Spectrometry (HRMS)

2.0K
The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
2.0K
Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

1.8K
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and signal-to-noise ratio for the analyte. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.
Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called collision-induced...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Describing the Utility of Fungal Blood Cultures in Patients Hospitalized at a Large Pediatric Academic Center.

The Pediatric infectious disease journal·2026
Same author

School masking and COVID-19 community transmission: a synthetic control study.

Health affairs scholar·2025
Same author

National Trends in Dexrazoxane and Cardiovascular Health Care Utilization for Children With Acute Myeloid Leukemia.

JAMA oncology·2025
Same author

Fluoroquinolone Susceptibility and Comparative Outcomes of Gram-negative Bloodstream Infection in Pediatric Patients With Hematologic Malignancy.

Journal of the Pediatric Infectious Diseases Society·2025
Same author

AML Care at Home: An Evidence-Based Toolkit to Personalize the Care Setting for Recovery From Pediatric AML Chemotherapy.

JCO oncology practice·2025
Same author

School masking and COVID-19 community transmission: a synthetic control study.

medRxiv : the preprint server for health sciences·2025

Related Experiment Video

Updated: Nov 14, 2025

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

4.3K

Low-pressure multipass Raman spectrometer.

Alfredo D Tuesta, Brian T Fisher, Aaron W Skiba

    Applied Optics
    |March 10, 2021
    PubMed
    Summary
    This summary is machine-generated.

    A new fiber-coupled Raman spectroscopy system enables nonintrusive temperature measurements in low-pressure propulsion plumes. This compact, robust diagnostic overcomes optical access limitations in vacuum chambers, crucial for thruster design and optimization.

    More Related Videos

    Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
    09:57

    Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems

    Published on: February 10, 2020

    7.4K
    Highly-Multiplexed Tissue Imaging with Raman Dyes
    07:18

    Highly-Multiplexed Tissue Imaging with Raman Dyes

    Published on: April 21, 2022

    3.1K

    Related Experiment Videos

    Last Updated: Nov 14, 2025

    Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
    09:57

    Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

    Published on: July 25, 2022

    4.3K
    Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
    09:57

    Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems

    Published on: February 10, 2020

    7.4K
    Highly-Multiplexed Tissue Imaging with Raman Dyes
    07:18

    Highly-Multiplexed Tissue Imaging with Raman Dyes

    Published on: April 21, 2022

    3.1K

    Area of Science:

    • * Propulsion Engineering
    • * Spectroscopic Diagnostics
    • * Fluid Dynamics

    Background:

    • * Accurate thermodynamic property measurements are essential for advancing propulsion system design and optimization.
    • * Traditional laser-based diagnostics face challenges in optically inaccessible, low-pressure environments like vacuum chambers.
    • * Existing facilities often lack the space and stability for complex diagnostic setups.

    Purpose of the Study:

    • * To develop a high-throughput, nonintrusive diagnostic system for measuring thermodynamic properties in challenging propulsion test environments.
    • * To overcome limitations in optical access and low number densities characteristic of vacuum chamber plume testing.
    • * To create a compact, versatile, and robust system suitable for typical propulsion testing facilities.

    Main Methods:

    • * Development of a fiber-coupled, multipass cell, spontaneous Raman scattering spectroscopy system.
    • * Utilization of H2 rotational Raman thermometry for accurate temperature measurements.
    • * Proof-of-principle testing conducted in low-pressure environments down to 67 Pa (500 mTorr).

    Main Results:

    • * Successful demonstration of nonintrusive temperature measurements in low-pressure environments (as low as 67 Pa).
    • * Validation of the fiber-coupled multipass cell design for overcoming optical access limitations.
    • * Evaluation of techniques to maintain signal-to-noise ratio at reduced pressures.

    Conclusions:

    • * The developed fiber-coupled Raman spectroscopy system provides a viable solution for quantitative thermodynamic measurements in challenging propulsion plume environments.
    • * The system's compact and robust design makes it suitable for integration into typical propulsion testing facilities.
    • * The diagnostic shows potential for further quantitative measurements beyond temperature.