Related Experiment Video
Updated: Nov 14, 2025

16:31
Simple Elimination of Background Fluorescence in Formalin-Fixed Human Brain Tissue for Immunofluorescence Microscopy
Published on: September 3, 2017
17.7K
Construction and theoretical insights into the ESIPT fluorescent probe for imaging formaldehyde in vitro and in vivo
Anyao Bi1, Min Liu, Shuai Huang
1Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, P. R. China. wbzeng@hotmail.com wbzeng@csu.edu.cn.
Abstract:
We report the first ESIPT-based probe ABTB, for the highly sensitive and selective imaging of formaldehyde (FA). The various theoretical calculations have been systematically performed, and clearly unravel the lighting mechanism of the fluorescent probe for FA. Additionally, the probe was successfully applied in monitoring endogenous FA in the brain of AD mice.

