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Updated: Nov 14, 2025

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Monitoring Astrocyte Reactivity and Proliferation in Vitro Under Ischemic-Like Conditions
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A totally OSM gift to astrocytes relieves inflammation
Angela A Wang1, Jennifer L Gommerman1
1Department of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada.
Immunity
|March 10, 2021
Abstract:
Dectin-1 is known for promoting anti-fungal responses through the signaling molecule Card9. In this issue of Immunity, Deerhake et al. now report that during autoimmune neuroinflammation, Dectin-1 can promote a neuroprotective feed-forward pathway through Card9-independent upregulation of Oncostatin M.
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