Isolation of Mycobacterium talmoniae from a patient with diffuse panbronchiolitis: a case report
Tomoko Suzuki1, Miwako Saitou2, Yuriko Igarashi3
1Department of Infectious Disease and Pulmonary Medicine, Aizu Medical Center, Fukushima Medical University, 21-2 Maeda, Tanisawa, Kawahigashimachi, Aizuwakamatsu, Fukushima, 969-3492, Japan. suzukito@fmu.ac.jp.
Background:
Mycobacterium (M) talmoniae isolated from a patient with cystic fibrosis was first described in 2017, and cases of M. talmoniae remain exceedingly rare.
Case Presentation:
A 51-year-old woman had respiratory symptoms for 10 years. Diffuse panbronchiolitis (DPB) was detected at the first visit at our hospital. A cavity lesion in the apex of the left lung was found, and sputum and bronchoalveolar lavage fluid were acid-fast bacillus (AFB) smear- and culture-positive besides Pseudomonas aeruginosa. M. talmoniae was finally identified, and the standard combination therapy for non-tuberculous mycobacteria (NTM) was administered for 2 y referring to the drug-susceptibility test. Thereafter, the AFB culture was negative, the wall thickness of the lung cavity was ameliorated, and oxygen saturation improved.
Conclusions:
We encountered a rare case of M. talmoniae with DPB, for which standard combination therapy was effective. M. talmoniae may be considered a potential pathogen of lung disease, especially in patients with bronchiectatic lesions.
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