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Updated: Nov 14, 2025
Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus
Published on: March 28, 2025
Relationship between hepatic grayish-white solid nodules in horses imported from Canada and larval Echinococcus
Tatsuro Hifumi1, Tetsuya Tanaka1, Emmanuel Pacia Hernandez1
1Transboundary Animal Diseases Research Center (Hifumi), Laboratory of Veterinary Histopathology (Hifumi, Hatai, Miyoshi), Laboratory of Infectious Diseases (Tanaka, Hernandez), Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan; Kumamoto Prefectural Meat Inspection Office, 1314 Sosaki, Shichijo-machi, Kikuchi, Kumamoto, 861-1344, Japan (Akioka, Yamada, Imamura).
Abstract:
Histopathological and genetic examinations were conducted on grayish-white solid hepatic nodules in 150 horses imported from Canada, in order to investigate larval Echinococcus multilocularis infection. Ten of the 150 horses (6.7%) were diagnosed with alveolar hydatid disease. The sequences of the mitochondrial cytochrome b genes obtained from all 10 polymerase chain reaction positive samples had 99 to 100% identity with the European haplotype E1 of E. multilocularis. Therefore, we concluded that the infections likely originated in Canada.
