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Demonstration of Improved Renal Congestion After Heart Failure Treatment on Renal Perfusion Imaging With

Kaoru Komuro1, Kyo Shimazu1, Takuya Koizumi1

  • 1Department of Cardiology, National Hospital Organization Hakodate National Hospital Hakodate Japan.

Circulation Reports
|March 11, 2021
PubMed

Insights

Contrast-enhanced ultrasonography (CEUS) effectively quantifies renal congestion in congestive heart failure (CHF) patients. CEUS reveals improved renal blood volume and perfusion after CHF treatment.

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • Renal congestion is a key factor in congestive heart failure (CHF) pathophysiology.
  • Accurate quantification of renal congestion is crucial for managing CHF patients.

Purpose of the Study:

  • To evaluate the utility of contrast-enhanced ultrasonography (CEUS) in quantifying renal congestion in CHF patients.
  • To assess changes in renal perfusion and blood volume before and after treatment for CHF.

Main Methods:

  • CEUS was performed on 11 CHF patients and 9 healthy controls at baseline and post-treatment.
  • Key parameters measured included time to peak intensity (TTP) for perfusion and relative contrast intensity (RCI) for blood volume.
  • Analysis focused on renal cortex and medulla.

Main Results:

  • CHF patients exhibited significantly prolonged TTP and lower RCI in both renal cortex and medulla compared to controls.
  • Following CHF treatment, RCI significantly increased in both cortex and medulla.
  • TTP decreased in the renal cortex post-treatment, but remained unchanged in the medulla.

Conclusions:

  • CEUS is a viable imaging technique for visualizing and quantifying renal congestion in CHF.
  • CEUS-derived parameters reflect changes in renal hemodynamics associated with CHF and its treatment.

Keywords:
ContrastHeart failureRenal congestionRenal perfusionUltrasonography

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