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Hypertrophic cardiomyopathy: insights from extracellular volume mapping

Silvia Castelletti1, Katia Menacho2, Rhodri H Davies2

  • 1Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin, via Pier Lombardi 22, 20135 Milan, Italy.

European Journal of Preventive Cardiology
|March 11, 2021
PubMed
Summary

No abstract available in PubMed .

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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