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Regional differences in office and self-measured home heart rates in Asian hypertensive patients: AsiaBP@Home study
Naoko Tomitani1, Satoshi Hoshide1, Peera Buranakitjaroen2
1Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.
Insights
South Asian hypertensive patients exhibit higher resting heart rates (RHRs) compared to East and Southeast Asians. This finding suggests a need for region-specific strategies to prevent cardiovascular disease.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Elevated resting heart rate (RHR) is a significant predictor of cardiovascular disease (CVD), heart failure, and mortality.
- Interventions to lower high RHR have been linked to reduced coronary events.
- Cardiovascular disease prevalence varies across diverse Asian regions.
Purpose of the Study:
- To investigate regional differences in RHR among hypertensive patients across East Asia, Southeast Asia, and South Asia.
- To compare self-measured RHR values using a standardized home blood pressure monitoring device across these regions.
- To determine if RHR regional tendencies differ from blood pressure (BP) regional tendencies.
Main Methods:
- Analysis of data from the AsiaBP@Home study, including 1443 hypertensive patients.
- Categorization of participants into three Asian regions: East Asia (N=595), Southeast Asia (N=680), and South Asia (N=168).
- Utilized a validated Omron HEM-7130-AP/HEM-7131-E home BP monitoring device for RHR measurements.
Main Results:
- South Asian patients demonstrated significantly higher RHR values compared to those in East and Southeast Asia.
- This regional RHR tendency was distinct from the observed regional BP tendencies.
- Adjusted analyses confirmed highest office and home RHR values in South Asia across all measurement times (morning and evening).
Conclusions:
- Findings indicate that South Asian hypertensive patients have the highest RHRs among the studied Asian regions.
- The observed differences in RHR suggest potential benefits of tailored clinical strategies for CVD prevention in specific Asian regions.
- Regionally specific approaches may be necessary for effective cardiovascular disease risk management in Asia.
Abstract:
Increased heart rate is a predictor of cardiovascular disease, heart failure, and all-cause mortality. In those with high heart rates, interventions for heart rate reduction have been associated with reductions in coronary events. Asia is a diverse continent, and the prevalences of hypertension and cardiovascular disease differ among its countries. The present analysis of AsiaBP@Home study data investigated differences among resting heart rates (RHRs) in 1443 hypertensive patients from three Asian regions: East Asia (N = 595), Southeast Asia (N = 680), and South Asia (N = 168). This is the first study to investigate self-measured RHR values in different Asian countries/regions using the same validated home BP monitoring device (Omron HEM-7130-AP/HEM-7131-E). Subjects in South Asia had higher RHR values compared with the other two regions, and the regional tendency found in RHR values was different from that found in BP values. Even after adjusting for age, sex, BMI, habitual alcohol consumption, current smoking habit, shift worker, hyperlipidemia, diabetes, chronic kidney disease, history of heart failure, and beta-blocker use, both office and home RHR values in South Asia were the highest among Asia (mean values ± SE of office: East Asia [E] 75.2 ± 1.5 bpm, Southeast Asia [Se] 76.7 ± 1.5 bpm, South Asia [S] 81.9 ± 1.4 bpm; home morning: [E] 69.0 ± 1.2 bpm, [Se] 72.9 ± 1.2 bpm, [S] 74.9 ± 1.1 bpm; home evening: [E] 74.6 ± 1.2 bpm, [Se] 78.3 ± 1.2 bpm, [S] 83.8 ± 1.1 bpm). Given what is known about the impact of RHR on heart disease, our findings suggest the possible benefit of regionally tailored clinical strategies for cardiovascular disease prevention.
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