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Acute posterior multifocal placoid pigment epitheliopathy and cerebral vasculitis
C A Wilson1, E A Choromokos, R Sheppard
1Department of Ophthalmology, University of Cincinnati College of Medicine, OH.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|June 1, 1988
Abstract:
Four cases of suspected cerebral vasculitis have been described in association with acute posterior multifocal placoid pigment epitheliopathy, but none was confirmed histopathologically. We describe a patient who developed fatal cerebral vasculitis after placoid pigment epitheliopathy. Histopathologic data revealed a focal granulomatous inflammation of medium-sized arteries in the leptomeninges. Multinucleated giant cells were a conspicuous part of the inflammatory reaction. The cause of both placoid pigment epitheliopathy and cerebral vasculitis remains obscure.