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Neuropeptide Y stimulates inositol phospholipid hydrolysis in rat brain miniprisms
1American Cyanamid Company, Medical Research Division, Lederle Laboratories, Pearl River, NY 10965.
Brain Research
|April 19, 1988
Abstract:
Neuropeptide Y (NPY) stimulates the hydrolysis of inositol phospholipid in rat brain miniprisms. The stimulation was two-fold in the frontal cortex and in the hippocampus, and 1.5-fold in the striatum. NPY produced no significant effects on basal inositol monophosphate levels in hypothalamic miniprisms. However, those basal levels were much higher than in the other brain regions.