Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased expression of autophagy-related proteins in keratocystic odontogenic tumours: its possible association with growth potential.

The British journal of oral & maxillofacial surgery·2014
Same author

The sabotage of the bacterial transcription machinery by a small bacteriophage protein.

Bacteriophage·2014
Same author

In vivo and in vitro evidence of the sex-dependent pharmacokinetics and disposition of G004, a potential hypoglycemic agent, in rats.

European journal of drug metabolism and pharmacokinetics·2014
Same author

Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling.

Stem cell research & therapy·2014
Same author

Sequential release of autophagy inhibitor and chemotherapeutic drug with polymeric delivery system for oral squamous cell carcinoma therapy.

Molecular pharmaceutics·2014
Same author

Proteomic analysis of differentially expressed skin proteins in iRhom2(Uncv) mice.

BMB reports·2014

Related Experiment Video

Updated: Nov 14, 2025

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.8K

Comparison of Two Methods for Presurgical Volumetric Evaluation of Alveolar Cleft Bone Defects Using Computer-Aided

Bing Liu1, Ning B Yin1, Ran Xiao2

  • 1Center for Cleft Lip and Palate Treatment, Plastic Surgery Hospital.

The Journal of Craniofacial Surgery
|March 11, 2021
PubMed
Summary

Two computer-aided engineering methods accurately assess alveolar cleft volumes for bone grafting. Both mirror-reversed and subtraction techniques are reliable, with the subtraction method offering broader surgical simulation potential.

More Related Videos

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures
09:10

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

2.0K
Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques
07:16

Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques

Published on: October 20, 2023

1.6K

Related Experiment Videos

Last Updated: Nov 14, 2025

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.8K
Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures
09:10

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

2.0K
Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques
07:16

Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques

Published on: October 20, 2023

1.6K

Area of Science:

  • Oral and Maxillofacial Surgery
  • Biomedical Engineering
  • Radiology

Background:

  • Accurate volumetric assessment of alveolar clefts is crucial for planning secondary alveolar bone grafting (SABG).
  • Computer-aided engineering (CAE) offers advanced tools for precise 3D analysis.
  • Reducing donor site morbidity relies on precise graft volume estimation.

Purpose of the Study:

  • To investigate and compare two CAE-based presurgical volumetric assessment methods for alveolar clefts.
  • To evaluate the accuracy, reliability, and efficiency of the mirror-reversed technique and the subtraction method.
  • To determine the clinical utility of these methods in planning SABG.

Main Methods:

  • Analysis of preoperative computed tomography (CT) scans from 20 patients with unilateral alveolar clefts using CAE software.
  • Calculation of cleft defect volumes using the mirror-reversed technique (reversing non-cleft to cleft side).
  • Calculation of cleft defect volumes using the subtraction method (simulated cleft filling).

Main Results:

  • Both mirror-reversed and subtraction methods yielded comparable mean defect volumes (1.27 ± 0.35 cm³ vs. 1.23 ± 0.32 cm³).
  • Calculation times were efficient for both methods (11.80 ± 1.79 s vs. 9.43 ± 1.35 s).
  • Bland-Altman analysis confirmed the equivalence of both methods for defect assessment, showing high precision and reproducibility.

Conclusions:

  • Both mirror-reversed and subtraction methods are reliable, precise, and time-efficient tools for presurgical alveolar cleft volume assessment.
  • These CAE-based methods facilitate accurate preparation of bone substitutes for SABG.
  • The subtraction method demonstrates greater potential for simulating intraoperative bone grafting procedures.