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Conjunctival Carcinomas Arising in the Anophthalmic Socket.
Paola Bonavolontà1, Federica Fossataro2, Fausto Tranfa2
1Department of Neuroscience, and Reproductive Sciences and Odontostomatology, Maxillofacial Surgery, Section.
The Journal of Craniofacial Surgery
|March 11, 2021
Summary
Conjunctival carcinomas in anophthalmic sockets are rare but serious. Regular eye exams and prosthesis care are crucial for early detection and management of these tumors.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Conjunctival carcinomas are rare malignancies.
- An anophthalmic socket can develop conjunctival carcinomas, often associated with chronic inflammation or prosthesis issues.
Purpose of the Study:
- To report the management and outcomes of patients with conjunctival carcinomas arising in the anophthalmic socket.
Main Methods:
- Retrospective analysis of clinical records of 4 patients diagnosed with conjunctival carcinoma in the anophthalmic socket between January 2014 and December 2019.
- Surgical excision and, in one case, orbital exenteration were performed.
- Tumor staging utilized the American Joint Committee on Cancer TNM staging system.
Main Results:
- Four male patients (median age 58) with a history of enucleation (trauma or retinoblastoma) were included.
- The most common tumors were squamous cell carcinoma (2 cases), followed by mucoepidermoid carcinoma and carcinoma in situ.
- Median follow-up was 15 months, with one patient requiring orbital exenteration due to high-grade cancer.
Conclusions:
- Conjunctival carcinomas in anophthalmic sockets require careful management due to their severity and rarity.
- Mandatory ophthalmological examination of the socket and prosthesis revision are essential to detect and eliminate irregularities that may promote chronic inflammation and tumor growth.
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