Cold panniculitis in children (Haxthausen's disease)

Area of Science:

• Dermatology
• Pediatrics

Background:

• Cold panniculitis is an underrecognized inflammatory condition affecting subcutaneous fat.
• It predominantly impacts infants and young children.

Observation:

• Clinical presentation includes erythematous, indurated plaques or nodules.
• Lesions typically appear on the face, particularly the cheeks and chin.
• Onset follows exposure to severe cold temperatures.

Findings:

• Cold panniculitis is likely more common than previously thought.
• The condition is characterized by localized fat necrosis due to cold injury.
• Histopathological examination reveals characteristic findings of panniculitis.

Implications:

• Increased awareness among clinicians can lead to earlier diagnosis.
• Understanding the etiology aids in preventive strategies for infants.
• Further research can elucidate underlying mechanisms and long-term outcomes.