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Updated: Nov 14, 2025
07:15
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
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Gut bacteria formation and influencing factors
Jing Yang1, Jin'en Wu1, Yating Li1
1State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, CAAS, 1 Xujiaping, Chengguan District, Lanzhou 730046, China.
FEMS Microbiology Ecology
|March 11, 2021
Summary
Modern lifestyles, including diet and antibiotics, significantly alter the gut microbiota. Understanding these gut bacteria changes is crucial for maintaining human health and preventing diseases.
Area of Science:
- Microbiology
- Human Health
- Gut Microbiome Research
Background:
- The gut microbiota is integral to human health.
- Modern lifestyle factors like diet and antibiotic use extensively impact gut bacteria.
- These alterations can lead to gut microbiota-orchestrating disorders.
Purpose of the Study:
- To review the effects of various factors on gut bacteria.
- To enhance understanding of gut bacteria's significance to human health.
- To identify strategies for preventing or treating gut microbiota-related diseases.
Main Methods:
- Literature review of factors influencing gut bacteria.
- Analysis of the impact of geographic location, age, diet, antibacterial drugs, psychological state, and exercise.
- Synthesis of current knowledge on gut microbiota modulation.
Main Results:
- Dietary habits (high-sugar, high-fat) significantly affect gut bacteria composition.
- Antibacterial drug usage profoundly alters the gut microbial ecosystem.
- Factors such as age, geography, exercise, and psychological state also modulate gut bacteria.
Conclusions:
- Gut microbiota composition is dynamic and influenced by multiple external and internal factors.
- Understanding these influences is key to appreciating the gut microbiome's role in health.
- Targeting lifestyle and medical interventions can help manage gut microbiota and prevent associated diseases.
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