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Updated: Nov 14, 2025

Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh
Published on: September 11, 2021
Abdominal wall reconstruction using biosynthetic absorbable mesh in high-risk complex ventral hernia.
David Finch1, Sajid Mehmood1, Joseph Varghese1
1Department of General Surgery, Royal Bolton Hospital, Bolton, United Kingdom.
Polyglycolic acid (PGA):trimethylene carbonate (TMC) biosynthetic mesh shows promising results for complex ventral hernia repair in high-risk patients. This study found a low recurrence rate and improved quality of life, warranting further investigation.
Area of Science:
- Abdominal wall reconstruction
- Surgical mesh technology
- Hernia repair outcomes
Background:
- Biosynthetic mesh may offer advantages over traditional meshes for complex ventral hernias.
- This study evaluates polyglycolic acid (PGA):trimethylene carbonate (TMC) mesh in high-risk patients.
- The mesh was used for midline fascial reinforcement in single-stage repairs.
Purpose of the Study:
- To evaluate the performance of PGA:TMC biosynthetic mesh.
- To assess outcomes in high-risk patients undergoing complex ventral hernia repair.
- To analyze recurrence rates, surgical site infections, and quality of life.
Main Methods:
- Retrospective review of 56 patients from May 2013 to August 2017.
- Open, single-stage complex ventral hernia repair using PGA:TMC mesh.
- Quality of life assessed using the Short Form-12 (SF-12) instrument.
Main Results:
- A low overall hernia recurrence rate of 3.6% was observed.
- Surgical site infection occurred in 26.8% of patients.
- Significant improvements in both physical and mental components of quality of life were reported.
Conclusions:
- Biosynthetic mesh demonstrates promising early outcomes in complex ventral hernia repair.
- Further well-controlled studies with longer follow-up are necessary.
- This study contributes data on a large series of abdominal wall reconstructions using biosynthetic mesh.
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