Epithelial morphology of duodenal bulb and Campylobacter-like organisms

We have carried out ultramicroscopical investigations on 30 patients with endoscopical aspects of congestive or erosive duodenitis associated or not with bulbar ulcer in relation to the presence of Campylobacter-like organisms (CLO), considered as a possible etiologic agent of peptic disease. Bacteria were found in all of the 14 patients with duodenal ulcer and in only five patients without ulcer. The ultrastructural studies provided elements for the evaluation of epithelial colonization of the duodenal bulb by CLO and which may lead to a new interpretation of gastric metaplasia.