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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

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Factors Linked to Chronic Kidney Disease Among Stroke Survivors in Ghana

Fred Stephen Sarfo1, Martin Agyei1, Isaac Ogyefo1

  • 1Nkrumah University of Science and Technology, School of Medical Sciences, Department of Medicine, Private Mail Bag, Kumasi, Ghana; Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|March 11, 2021
PubMed

Insights

One in five stroke survivors in Ghana have chronic kidney disease (CKD). This study identified age, male sex, rural residence, and antihypertensive use as key risk factors for CKD in this population.

Area of Science:

  • Nephrology
  • Neurology
  • Public Health

Background:

  • Chronic kidney disease (CKD) is linked to adverse outcomes in stroke survivors.
  • Stroke and CKD incidence are rising in Africa, yet CKD burden in stroke survivors remains understudied.
  • This research addresses the knowledge gap in sub-Saharan Africa.

Purpose of the Study:

  • To determine the prevalence of CKD among stroke survivors in Ghana.
  • To identify factors associated with CKD in this patient group.
  • To stratify findings by primary stroke type.

Main Methods:

  • Prospective data collection from stroke survivors at a Ghanaian outpatient clinic (Jan 2018-Mar 2020).
  • Estimated glomerular filtration rate (eGFR) calculated using CKD-EPI formula; CKD defined as eGFR <60ml/min.
  • Multiple logistic regression used to identify factors associated with CKD.

Main Results:

  • A prevalence of 21.0% (159/759) for CKD was observed among stroke survivors.
  • Significant CKD associations included: higher age (per decile rise), male sex, rural dwelling, prior antihypertensive use, and number of antihypertensive classes.
  • Individuals with CKD were significantly older (61.6 vs 57.5 years).

Conclusions:

  • Approximately 21% of stroke survivors in this Ghanaian cohort exhibit signs of CKD.
  • Interventions targeting blood pressure management and rural populations are recommended.
  • Addressing CKD in stroke survivors may reduce the risk of poor health outcomes.
Abstract

Keywords:
AfricaAtherosclerotic riskNephronsVascular risk

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