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Next-generation ingestible devices: sensing, locomotion and navigation.

Fahad N Alsunaydih1,2, Mehmet R Yuce1

  • 1Department of Electrical and Computer Systems Engineering, Monash University, Melbourne, VIC, Australia.

Physiological Measurement
|March 11, 2021
PubMed
Summary

Active wireless capsule endoscopy (WCE) aims to improve gastrointestinal diagnostics by enabling controlled movement for targeted drug delivery and precise abnormality localization. This technology enhances patient care and diagnostic accuracy.

Keywords:
bio-inspired mechanismscapsule endoscopy locomotionelectromagnetic platformgastrointestinal (GI) tractingestible sensorsswallowable deviceswireless capsule endoscopy (WCE)

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Area of Science:

  • Biomedical Engineering
  • Gastroenterology
  • Medical Devices

Background:

  • Wireless capsule endoscopy (WCE) is a vital tool for non-invasive gastrointestinal (GI) tract exploration.
  • Current WCEs are passive, limiting their application in targeted therapies and precise diagnostics.
  • Ingestible sensing technology offers a platform for monitoring physiological and biological activities within the body.

Purpose of the Study:

  • To review and compare current technological developments in ingestible sensing, locomotion, and navigation for WCEs.
  • To explore key features for next-generation active WCEs.
  • To evaluate methods based on safety, velocity, design complexity, control, and power consumption.

Main Methods:

  • Comparative analysis of existing ingestible device technologies.
  • Exploration of essential features for active WCE implementation.
  • Evaluation of locomotion and navigation methods for ingestible devices.

Main Results:

  • Significant advancements in ingestible sensing capabilities.
  • Challenges remain in achieving controlled locomotion and navigation within the GI tract.
  • Active WCEs offer potential for improved drug delivery, localization, and reduced diagnostic time.

Conclusions:

  • Active ingestible WCEs are crucial for enhancing diagnostic capabilities and therapeutic applications in gastroenterology.
  • Further research and development are needed to overcome locomotion and control challenges.
  • Next-generation active WCEs promise safer, more efficient, and targeted GI diagnostics and treatments.