Related Experiment Video
Updated: Nov 14, 2025

Measurement of Lifespan in Drosophila melanogaster
Published on: January 7, 2013
Comparative Methodologic and Practical Considerations for Life Expectancy as a Public Health Mortality Measure
Anne M Roubal1, Elizabeth A Pollock1, Keith P Gennuso1
15229372884 County Health Rankings & Roadmaps, University of Wisconsin Population Health Institute, University of Wisconsin-Madison, Madison, WI, USA.
Life expectancy calculations for US counties reveal significant variation. This metric strongly correlates with other health indicators and differs from years of potential life lost before age 75 (YPLL-75) and premature age-adjusted mortality (PAAM).
Area of Science:
- Public Health
- Biostatistics
- Demography
Background:
- Life expectancy is a key public health metric for assessing mortality across populations.
- Commonly used length-of-life metrics include years of potential life lost before age 75 (YPLL-75) and premature age-adjusted mortality (PAAM).
- Methodological differences, data availability, and age-specific risks can influence metric selection.
Purpose of the Study:
- To calculate life expectancy at the US county level.
- To compare life expectancy calculations with YPLL-75 and PAAM.
- To explore associations between life expectancy and other health measures.
Main Methods:
- Utilized National Center for Health Statistics death data (2015-2017) and County Health Rankings & Roadmaps data (2019).
- Calculated county-level life expectancy using an abridged life table and the Chiang method.
- Employed studentized residuals to identify discordant metric values and correlations to test associations with health factors.
Main Results:
- Life expectancy varied widely across 3073 US counties (62.4 to 98.0 years; mean 77.4 years).
- Strong negative correlations were observed between life expectancy and YPLL-75 (r = -0.91) and PAAM (r = -0.95).
- Life expectancy associated with health factors like smoking, employment, and education; discordant values related to differing age structures.
Conclusions:
- Life expectancy calculations provide valuable insights into county-level mortality.
- The choice of length-of-life metric should consider methodological factors and audience communication needs.
- Understanding variations in life expectancy and its correlates is crucial for targeted public health interventions.
More Related Videos
Related Concept Videos
Applications of Life Tables
Life Tables
Actuarial Approach
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Comparing the Survival Analysis of Two or More Groups
Kaplan-Meier Approach
Assumptions of Survival Analysis

